Tofranil (Imipramine): A Beacon of Hope for Mental Health

Generic Tofranil (Imipramine 25 mg) guide:

More facts about Generic Tofranil (Imipramine 25 mg):

What is the medication you are offered to buy as Generic Tofranil?

Tofranil is nothing more than a brand name that is used for one of the oldest antidepressants Imipramine. The active substance, Imipramine, was developed in the 1950s but even today it is widely used for the therapy of depression and especially severe depression resistant to other antidepressants as this particular medication is considered the most potent one. The substance is included in the class of tricyclic antidepressants and is sold with a prescription in the U.S. and the UK. However, it is sold worldwide under a variety of trade names and frequently can be bought over-the-counter. The names you can find this medication under are Antideprin, Dimipressin, Dynaprin, Estraldine, Eupramin, Imavate, Imipramina, Imiprin, Imizin, Impril, Intalpram, Iramil, Melipramine, Norfranil, Pramine, Prazepine, Promiben, and many others. Together these preparations are called generics of Tofranil or generics of Imipramine.

It is possible for the other pharmaceutical companies to manufacture the same medications because the exclusive right of the drug developer has already expired. As for the lower price of generics, their creation and distribution are supported by the World Health Organization for the purpose of making the most efficient treatment affordable to anyone.

Why is generic priced so much cheaper than the bran drug?

Although generics gain more and more popularity, many people are still hesitant to purchase them because they believe that their low price indicates the lower quality. In fact, these medications are priced reasonably while the branded medications are highly overpriced. Indeed, the generic manufacturers do not invest in research and development but considering that the medication was discovered more than 60 years ago, the cost of research paid back multiple times and the branded medication would need to be priced cheaper.

The quality of the generic medications is rigorously tested and verified before the medications are approved and released onto the market. So do not worry about the quality and efficacy of the pills when you get the medication from a reputable vendor like our online pharmacy.

In order to be sure that you obtain the right medication when you buy Generic Tofranil, you should check the active component name that is always obligatorily indicated below the trade name and is Imipramine.

When should I buy Generic Tofranil?

This particular antidepressant is used for depressive states accompanied by apathy and inhibition of thought activity as it also has a stimulating effect. Make sure you don’t use it if your condition is accompanied by anxiety, nervousness, and agitation as Imipramine can only worsen the condition and cause the development of mania or hypomania. Instead, you should look for antidepressants with the sedative, i.e. calming effect. However, whatever your diagnosis and symptoms are, it is always better to consult a therapist before you buy Imipramine even though you can get it without a prescription from our online pharmacy.

The indications for the preparation use are depressive states of various etiology (cause), asthenic-depressive syndrome, endogenous, involutional, climacteric, reactive, and alcoholic depression, depressive states in psychopathy and neurosis, panic disorder, and functional enuresis in children.

When should not I buy Imipramine?

Even if you believe that the symptoms you have or your diagnosis falls into the indications of this antidepressant use, you should check with your therapist that the medication is not contraindicated for you.

Imipramine is contraindicated in hypersensitivity (i.e. allergy or severe side effects from the drug use), liver and/or kidney dysfunction, coronary artery disease or cardiac ischemia, tachycardia, congestive heart failure, early post-infarction period, dysfunction of hemopoietic organs, diabetes, severe atherosclerosis, glaucoma (increased intraocular pressure), propensity to seizures, schizophrenia, epilepsy, glaucoma, prostate adenoma, atony of the bladder (loss of tonus), pregnancy, children's age (up to 6 years).

If you have any of these conditions or suspect them, inform your doctor before you buy Tofranil and start the therapy.

How should I use Generic Tofranil?

If you wonder whether the generic is used in the same manner as the branded medication, the answer is yes. If your therapist told you how you should take the medication exactly, you should follow his or her recommendations. If you don’t have precise instructions, you can follow the regular instruction provided below.

The initial dosage for adults is 25-50 mg a day taken 3-4 times a day. The treatment is started with the minimum dosage with subsequent dosage increase by 25 mg daily till the achievement of antidepressive effect. If the effect is achieved with a lower dosage than the maximum daily one, the further rise of the dose is not needed. The maximum daily dosage for adults in use at home is 200 mg. In a hospital, the maximum daily dosage can be raised to 300 mg for a short period of time.

Children aged from 6 to 12 should be administered 10-30 mg a day in two split intakes. Children older than twelve years should take 25-50 mg a day in split dosages. If the effect is insufficient and the medication is well-tolerated, the dosage can be gradually raised at a doctor’s discretion. The maximum daily dosage for children is 100 mg.

The use of the high doses is reasonable for 4-6 weeks. Then, the doses are gradually lowered till the minimum effective ones. The complete withdrawal of the medication is made with a gradual reduction of the dosages.

The therapy of nocturnal enuresis (bedwetting), depending on the age is in the range of 25-75 mg taken once a day one hour before bedtime.

Dosage adjustments of Generic Tofranil

For the people of elderly age (over 65), the maximum daily dosage is 100 mg a day. The treatment is started with 10 mg taken once a day with subsequent increase of the dosage till 30-50 mg or more a day till the optimal well-tolerable dosage.

Adverse reactions of Tofranil

When you buy Generic Imipramine and start using the pills for the first time, you should pay attention to your condition and in the occurrence of any malaise inform your therapist. The most common adverse effects are insomnia, fear enhancement, anxiety and agitation, activation of psychical symptoms of aggression in endogenous psychical disorder, dizziness, headache, nausea, increased sweating, rapid heart rate and others.

Besides, if the medication is used for bipolar disorder, it can contribute to the inversion of the depressive phase into mania or hypomania.

The medication can contribute to the development of insomnia and therefore is advised to be used for the treatment of depression in the first half of the day (till 3-4 PM).

With what preparations or substances Imipramine must not be combined?

When you order Tofranil, you should remember that you must not combine it with MAO inhibitors and/or alcohol or you can die from the adverse reactions caused by these combinations.

The medication also lowers the efficiency of Phenytoin.

The sedative and anticholinergic activity effects of the medication are enhanced in combined use with cholinolytic medications, phenothiazines, and benzodiazepines.

The effect of the majority of medications that affect the central nervous system is enhanced by Tofranil.

Here are provided the warnings about the most dangerous combinations of the medications but there are more negative interactions with the drug. For more complete information please read the label of the drug or consult your therapist if you currently take any pills, additives, vitamins, mixtures, and so on.

Generic Tofranil overdose signs and therapy

When you order Generic Tofranil, you should remember that it a potent medication which misuse can cause severe damage to your health or lead to death.

The symptoms of an overdose are dizziness, agitation, involuntary muscle contractions, seizures, stupor, irregular heartbeat, collapse, low arterial pressure, respiratory depression, cyanosis, vomiting, fever, and others.

If you suspect that you took a higher dosage than you should have, provoke vomiting. Then, take activated carbon. If you started developing the negative symptoms, immediately seek medical assistance.

Where to buy Tofranil?

At our online pharmacy you can order Imipramine without a prescription and at a cheap price. This will save our money not only on the pills but also the visits to your doctor for a prescription.

Tofranil shipping

Our med store ships internationally. If you need the medication urgently, you can order express shipping. If you want to save on the shipping, choose standard, cheaper option that takes a bit longer.