More facts about Generic Benicar (Olmesartan 10 mg):
Generic Benicar (Olmesartan 10 mg) guide:
Drug sold under the brand name Benicar and Generic Benicar is based on the active substance called Olmesartan. It is a medication used to reduce blood pressure in hypertension.
When should Benicar (Olmesartan) be used?
The medication is used alone or in combination with other drugs (possibly, diuretics) in hypertension or elevated blood pressure. If your doctor prescribes you Benicar (Olmesartan), you can buy Generic Benicar (Olmesartan) and use this cheaper identical medication instead.
What is the mechanism of action of Benicar (Olmesartan)?
Brand Benicar (Olmesartan) and Generic Benicar are prodrugs, i.e. they are transformed into the active substance only in the body under the influence of esterases in the intestinal mucosa and in the portal vein during the absorption in the digestive tract.
The medication is a potent selective antagonist of angiotensin 2 receptors. It inhibits the effect of angiotensin 2 that are induced by the At1 receptors and result in the blood vessels narrowing. The drug not only helps to dilate the blood vessels and therefore lowers the blood pressure but also contributes to the increased concentrations of renin (a protein and enzyme secreted by the kidneys that mediates arterial vasoconstriction), as well as to promotes a decrease in the concentration of aldosterone (mineralocorticoid hormone produced by the adrenal gland).
The intake of the daily dosage once a day ensures the effective and gentle blood pressure lowering which lasts for 24 hours. The maximum antihypertensive effect is achieved 8 weeks after the therapy start though the first persistent favorable effect is observed already during the first two weeks of the therapy with Generic Benicar.
How to use the generic drug?
There are many medications for the blood pressure lowering. Some of them are suitable even for children and pregnant women, and some are not. Make sure to clarify with your doctor whether the drugs based on Olmesartan are suitable for you before you buy Generic Benicar and start using it.
The generally recommended dosages are the following:
- Adults: the initial daily dose of Olmesartan is 10 mg a day. If the blood pressure is not lowered enough, the dose of the drug is raised to the optimal daily dosage of 20 mg. If necessary, the dose of the drug can be increased to the maximum of 40 mg per day. The drug is taken every day at the same time, regardless of food intake.
- Patients of advanced age: usually, there is no need for the dose adjustment for elderly patients. If it is necessary to increase the daily dosage to the maximum of 40 mg per day, the increase should be carried out under the constant monitoring of the blood pressure.
- Patients with mildly or moderately impaired kidney function (with creatinine clearance 20-60 milliliters per minute): the maximum daily dosage is 20 mg. To enhance of the blood lowering effect, the medication can be combined with Hydrochlorothiazide.
Whom the drug is contraindicated?
You should not buy Generic Benicar if you have allergy to the medication’s active or additional components. The drug must not be used during pregnancy and breastfeeding, in children and teenagers under 18 years of age.
If before the therapy with Generic Benicar (Olmesartan) a patient were undergoing an intensive therapy with diuretics, had a salt-free diet or suffered from diarrhea or vomiting, after the first intake he or she can suffer from hypotension (excessively lowered blood pressure) due to the decreased volume of circulating blood. Therefore, before starting the therapy, it is necessary to eliminate the possibility of oligemia (a decrease in volume of blood plasma).
The drug should be cautiously used by people with heart failure, kidney disease, renal artery stenosis of both or a single kidney, since there is a risk of developing acute hypotension, azotemia, oliguria, and acute renal failure. During the treatment of patients with impaired renal function, it is recommended to perform periodic monitoring of potassium and creatinine levels in the blood serum.
People with stenosis of the aortic or mitral valves or with obstructive hypertrophic cardiomyopathy should also be careful using the medication – stat with the lower dosages and if any side effects occur, stop the treatment immediately and contact their doctor for a consultation.
People with primary hyperaldosteronism are not responsive to the medication and should not use Olmesartan for the blood pressure lowering effect.
If the drug lowers the blood pressure excessively in people with congestive heart failure or atherosclerosis of cerebral vessels, the therapy should be terminated as it can lead to myocardial infarction or ischemic stroke.
What side effects can Benicar (Olmesartan) cause?
The possible adverse effects during the therapy with the drug include dizziness, chest pain, tachycardia, abdominal pain, dyspepsia, gastroenteritis, nausea, hypercholesterolemia, arthralgia, arthritis, myalgia, skin rash, peripheral edema, hyperuricemia, and others.
If you have any of these or other negative symptoms related to the drug use, seek medical assistance and stop using the drug immediately.
With what medications the drug should not be combined?
If you buy Generic Benicar (Olmesartan) and start using it, make sure to exclude other drugs for the blood pressure lowering as the combined effect may lead to hypotension.
The same excessive blood pressure lowering effect can be observed in the combined use with nonsteroidal anti-inflammatory drugs.
The drugs to reduce stomach acidity lower the effect of Olmesartan-based medications.
It is not advised to combine the drug with lithium-based medications as the toxic effect of the latter can be amplified.
To avoid hyperkalemia, it is not advised to use the medication with potassium-sparing diuretics and other drugs that can elevate the potassium levels in the body.
What should you do in the overdose with Benicar (Olmesartan)?
The common symptoms of the overdose include arterial hypotension that requires symptomatic treatment and hospitalization.
Is there a difference between the brand-name drug and the generic?
The drugs are identical. They are made using the same formula and components. They are made by the different pharmaceutical companies, hence the difference in the prices.
Millions of people from around the world prefer to buy Generic Benicar (Olmesartan) because the drug has absolutely the same effect as the brand-name medication but is priced several times cheaper.
Where to buy Benicar (Olmesartan) online?
In the majority of the U.S. pharmacies, you can buy both the brand-name drug and its generic version. Though, you would need a prescription from your doctor every time you need a refill. To avoid it, you can purchase the medication from our online pharmacy. Moreover, we set the lower prices on the same drugs as we are located outside the U.S. where the operational costs for a pharmacy are much lower.
Generic Benicar (Olmesartan) shipping by Rxshop
Whenever you are, we will ship your pills via standard or express shipping. We ship worldwide including the U.S. Naturally, the express shipping is more expensive but even opting for it you would save a lot not going to your doctor for a prescription. Regardless of the shipping method you chose, we will give you the tracking number using which you will see how your parcel moves.
If you buy pills for $170 or more at once, we will take the shipping expenses on us! Find out more about our bonuses and special offers at the FAQ section of our website.
Our doctor prescribes Olmesartan online for free, and there is no doctor’s consultation fee.
All orders of Olmesartan arrive in discrete unmarked parcels. We leave the shipment description blank.