Armodafinil can be called an improved version of Modafinil. It is based on the basically the same formula with slight changes that ensure the same effect as of Modafinil but rendered for longer time. Besides, due to the improvements made, the medication can be used in slightly lowered dosages than Modafinil. Armodafinil also has a very low potential for addiction development and therefore is safe to use in narcolepsy and other disorders that require continuous use of the pills.
Here you can see a comparison of key parameters of both drugs which can help you decide what suits you better.
Characteristics
Modafinil
Armodafinil
Class
analeptics; nootropics
analeptics; nootropics
Methods of administration
Oral pills
Oral pills
Time of intake
Before noon with or without meals.
Before noon with or without meals.
Dosage per day
200 mg
150 mg
Legal status
Rx-only
Rx-only
Indications for use
Narcolepsy, shift-work sleep disorder, obstructive sleep apnea
Narcolepsy, shift work sleep disorder, obstructive sleep apnea
Non-prescription uses
Attention deficit hyperactivity disorder, apathy associated with depression, Parkinson’s disease, cognitive functions impairment caused by brain trauma or surgery, chronic fatigue syndrome, opiate-related sleepiness, impaired cognitive functions due to chemotherapy, multiple sclerosis, enhancement of cognitive functions, weight loss aid, jet-lag, and others.
Attention deficit hyperactivity disorder, apathy associated with depression, Parkinson’s disease, cognitive functions impairment caused by brain trauma or surgery, chronic fatigue syndrome, opiate-related sleepiness, impaired cognitive functions due to chemotherapy, multiple sclerosis, enhancement of cognitive functions, weight loss aid, jet-lag, and others.
Commercial names
Modalert, Provigil, Modafinil, and others
Nuvigil, Artvigil, and others
Duration of action
Up to 10 hours
Up to 15 hours
Principle of action
The principle of Modafinil action isn’t fully understood yet. It is considered that it is due to the release of monoamines, especially catecholamine, norepinephrine and dopamine from synaptic clefts. Besides, Modafinil raises the level in histamine of the hypothalamus which is responsible for inhibition of sleepiness through natural mechanisms.
The principle of Armodafinil action is the same as of Modafinil. It is considered that it is due to the release of monoamines such as catecholamine, norepinephrine and dopamine from synaptic clefts. On top of that, Armodafinil elevates the level of histamine in the hypothalamus which is responsible for inhibition of sleepiness through natural mechanisms.
Possible adverse reactions
Adverse effects are rare and transient. They may include: Headache, anxiety, trouble falling asleep, and nausea. Severe adverse reactions can include allergic reactions such as anaphylaxis, Stevens-Johnson syndrome, or hallucinations.
Adverse effects are quite rare in the use of Armodafinil. They usually fade over a couple of days. Insomnia associated with the medication use can be prevented by the use of the pills in the morning only. The possible adverse reactions include: headache, dryness of the mouth, nausea, lightheadedness, and trouble falling asleep, hallucinations, euphoria, loss of appetite, and anxiety.
Prohibitions for use
Increased sensitivity to the tablets’ components; Pregnancy and lactation; Age under 18 years; Liver cirrhosis. Heart diseases and namely the left ventricular hypertrophy or mitral valve prolapse.
Increased sensitivity to the Armodafinil components; Pregnancy and lactation; Age under 18 years; Liver cirrhosis. Heart diseases and namely the left ventricular hypertrophy or mitral valve prolapse.
Pregnancy category
C (contraindicated, there hadn’t been studies of the drug use in pregnant women).
C (contraindicated, there hadn’t been studies of the drug use in pregnant women).
Overdose symptoms
Possible manifestations of an overdose include excitability, trouble falling asleep, anxiety, irritability, aggressive behavior, confusion, tremor, heart palpitations, sleep disturbances, vomiting, and diarrhea. The treatment is symptomatic.
Possible manifestations of an overdose include excitability, trouble falling asleep, anxiety, irritability, aggressive behavior, confusion, tremor, heart palpitations, sleep disturbances, vomiting, and diarrhea. The treatment is symptomatic./div>
Precautions for medication use
Modafinil should be taken only in the morning or the first half of the day or it can cause insomnia; The formulation negatively influences the effect of oral birth control so other adequate contraception methods are advised.
Armodafinil should be taken only in the morning or the first half of the day or it can cause insomnia; The formulation negatively influences the effect of oral birth control so other adequate contraception methods are advised.
Interactions
Modafinil is an inducer of a certain liver enzyme which means that the enzyme is more active when the drug is used. Due to this, some of the medications that are metabolized with CYP3A4 enzyme participation can be washed out faster.
Armodafinil, as well as Modafinil, is an inducer of CYP3A4 enzyme which means that the enzyme is more active when the drug is used. Due to this, some of the medications that are metabolized with its participation can be washed out faster.
Modafinil and Armodafinil both are perfect medications for narcolepsy and other conditions in which excessive sleepiness is a problem. Besides, since the medications are designed for long-term use, they are safe, do not cause addiction or any harm to the body or mental health. You can buy Armodafinil or Modafinil at our online drugstore at an attractive price and without Rx which makes the purchase even more beneficial.
