Mysoline (Primidone): A Proven Path to Seizure Management

Generic Mysoline (Primidon 250 mg) guide:

More facts about Generic Mysoline (Primidon 250 mg):

What is the medicine you can buy as Generic Mysoline?

The medication you know as Mysoline is quite a long-known anticonvulsant used since 1949. The active substance of the medication is Primidone. It is marketed under various trade names including Mysoline, Primidone, and others. If you need to find a cheaper version of the medicine but know only its branded name Mysoline, you can find it looking for Generic Mysoline. It is a common term used to help patients and pharmacists understand each when a patient wants to buy a certain medicine but from another manufacturer. Moreover, you can easily check whether you are offered to purchase the correct medication. All you need to do is to check the active substance name which is always indicated on the original package of the pills under the trade name. In case of Mysoline, the name of the active substance below the trademark is Primidone.

How is this possible that the same drug is cheaper? Is it inferior?

You may wonder why you can buy Generic Mysoline so much cheaper than the branded medicine. The thing is that the manufacturers of generic medications have ways to save on the production of the drugs without compromising their quality. For instance, they purchase the license to manufacture the same medicine without investing into research. As the main condition, they often are obliged to market their drugs outside the regions where the branded medicine is sold. To cut the costs even more, they locate their production facilities in the developing countries where the costs of utilities, labor force, and raw materials are less expensive. And as a final factor that makes these drugs less known and less expensive at the same time – the manufacturers do not advertise them. Following all of these simple rules, generic drug makers are able to save themselves and allow people who need certain preparations to save to. In some cases, generics are lifesavers. For instance, if an individual is diagnosed with a life-threatening condition but cannot afford the most effective and safe branded medicine they have two options: use outdated less effective meds or purchase generic with which basically anyone can have the best treatment.

If you still worry that generics are inferior, think about that no medicine is ever launched onto the market before it is tested for conformity to the original formula, safety level and effectiveness the same as of the branded medicine on which formula it is based on.

When should Mysoline be used?

The medication is prescribed for the therapy of various types of epilepsy. It is especially effective against big seizures and is less effective against focal, myoclonic, and akinetic seizures.

If you are diagnosed with epilepsy, you can buy Mysoline from our online pharmacy right away. But we highly recommend you to consult your doctor first.  The condition is treated with various medicines or a combination of them and only your doctor who knows your health history can decide what therapy would be optimal for you. Moreover, at our online pharmacy, you can find other anti-epileptic medicines too so it won’t be a problem to find an alternative and get all medicines that you need at once in one place and at an affordable price.

For whom the preparation is contraindicated?

Primidone and all drugs based on it are contraindicated for people with hypersensitivity to the pills’ ingredients including any barbiturates. It is also contraindicated for people with kidney or liver dysfunction, anemia, and leukopenia.

The pills must not be used also during pregnancy and breastfeeding.

The medicine is not recommended for children and elderly patients as these groups of patients can develop paradoxical agitation and motor anxiety.

How to use the pills of Generic Mysoline?

It is preferable that the treatment regimen would be chosen individually even if you buy Primidone without a prescription online. In some cases, it is enough to use the medicine as monotherapy while in others combined anticonvulsant therapy is required.

Generic Mysoline is usually advised to be taken two times a day. The starting dosage is 125 mg or a half of the standard pill once a day before sleep. Subsequently, every three days the dosage is increased by 125 mg to achieve the optimal therapeutic dosage of 500 mg a day or two pills a day. If the dosage isn’t sufficient for the suppression of seizures, the dosage is again gradually increased by 250 mg in adults every three days or by 125 mg in children from 3 to 9 years of age till the maximally effective and well-tolerated dosage.

The maximum tolerable dosage for children older than 9 years of age and adults is 1500 mg or 6 pills a day. For children between the ages of 3 and 9, this dosage is 1000 mg or 4 pills a day.

The average supporting (maintenance) dosages based on the age are the following:
- Children older than 9 years of age and adults – 750-1500 mg a day.
- Children between the age of 6 and 9 years – 750-1000 mg a day.
- Children between the age of 3 and 6 years – 500-750 mg a day.

The daily dosage is recommended to be divided into two equal parts and taken in the morning and in the evening. Some patients may need bigger dosages for the periods when the seizures occur more frequently. For instance, if the seizures predominantly occur during the night then the whole dosage or a bigger share of it should be taken before sleep. Also, if the seizures intensity and frequency are correlated with certain circumstances, for instance, during the menstruations they are more severe or often, then the dosage can be also increased for this period.

What adverse reactions can Mysoline (Primidone) cause?

When you buy Generic Primidone, you need to be ready that in the beginning of the therapy you may suffer from certain adverse reactions. Some of them fade over time but others require cancellation of the treatment with this particular anticonvulsant.

The most common adverse reactions that develop during the first days of the therapy and usually go away are sleepiness and apathy.

Other possible adverse reactions include vision impairment, nausea, headache, dizziness, vomiting, involuntary muscle contractions, nystagmus, and allergic reactions.

No matter what side effects you suffer from, you need to inform our health care provider right away as only a medical professional can assess whether they require the cancellation of the therapy or not.

Overdose identification and therapy

Since the dosages of the medication are increased gradually but with the half of the initial dosage or even the whole previously used dosage, an overdose can occur. The symptoms of an overdose are dizziness, nausea, involuntary or uncoordinated muscle contractions, loss of consciousness, and respiratory depression. Without any symptomatic measures and treatment it can lead to coma.

The first measures that you can undertake at home are to induce vomiting and take activated carbon. You should also seek emergency help as you may need gastric lavage and symptomatic treatment.

Interaction with other preparations and substances

When your health care provider appoints you the therapy with Mysoline or you plan to order Mysoline without prior consulting your doctor, you should check that you don’t use any medications this anticonvulsant is incompatible with.

Mysoline and its generics enhance the effect of sleeping pills, sulfonylureas, cyclophosphamide, and methotrexate.

It lowers the effect of paracetamol, glucocorticosteroids and mineralocorticosteroids, Griseofulvin, indirect anticoagulants, tricyclic antidepressants, chloramphenicol, cyclosporin, dacarbazine, digoxin glycosides, disopyramide, doxycycline, levothyroxine, metronidazole, mexiletine, quinidine, fenoprofen, vitamin D, aminophylline, caffeine, oestrifilina, theophylline, and oral contraceptives.

The depression of the central nervous system is enhanced in combination of the anticonvulsant with alcohol and other medicines that affect the nervous system.

Note that this list is incomplete. For more detailed and complete information please refer to the official instruction or consult a doctor or a pharmacist.

Where to buy Mysoline?

The medication should be taken for a long period of time, therefore, the best way to save on the treatment while receiving the best effect is to order Generic Mysoline from our online drugstore. You can do so at this web page. If you still have any questions or doubts about the medicine, please contact our pharmacists for more information.

Mysoline Delivery

We will deliver your order wherever you reside even if in your country the preparation is sold with a prescription only. We make sure to pack the pills in a discreet package.