More facts about Generic Imodium (Loperamide 2 mg):
Generic Imodium (Loperamide 2 mg) guide:
What is the drug sold as Imodium?
The name Imodium is owned by the large concern Johnson & Johnson. It is patented for the medication internationally known as Loperamide. The medication was discovered in the 1970s in Belgium. After the termination of the exclusive patent for production, a large number of generics appeared on the market. They are the same medications simply made by different companies and sold under different names. Some of the names the medication can be found under are Loperamide (by the name of the active substance), Lodcap, Roko, Diarr-Eze, Loperacap, Loperamida, Pepto Diarrhea Control, and others.
The medication is mainly used to stop spasms in the intestines and diarrhea either chronic or acute one regardless of the reasons that caused it. You can buy Imodium without a prescription as it is an emergency drug.
How do Imodium tablets act?
The medication has an anti-diarrhea activity that is due to the drug interaction with opiate receptors of the longitudinal and annular muscles of the intestinal wall and oppression of the release of acetylcholine and prostaglandins. It slows down the bowel movements and extends the time of passage of food through the intestines. It also elevates the tone of the anal sphincter helping to avoid any involuntary defecation, promotes retention of fecal masses and reduced urge to defecate. Inhibits the secretion of fluid and electrolytes in the lumen of the intestine and / or stimulates the absorption of salts and water from the intestine. In high doses can inhibit the secretion of hydrochloric acid in the stomach. Action of Loperamide develops quickly and lasts up to six hours.
The medication doesn’t cause dependency or lowered effect in the frequent or continuous use. However, during the tests on animals, in high doses uses, morphine-like dependence was observed.
The preparation is poorly absorbed from the intestinal tract, i.e. it doesn’t spread all over the body. Due to the high affinity to the receptors of the intestinal wall and a high degree of biotransformation at the "first passage" through the liver plasma level of unchanged substance after taking two mg of Loperamide hydrochloride - below 2 mg/ml. The max concentration of the active agent in the blood is observed within two and a half hours after the liquid form of the medicine and five hours after the intake of tablets.
Loperamide is metabolized in the liver and is excreted in bile and feces, and in a small amount in urine.
The medication starts to act quickly and the effect lasts for around six hours after which you can take additional doses.
Can you buy Generic Imodium in a place of the brand-name medication?
You don’t have any reason to get an expensive medication with an advertised name when you can buy Generic Imodium that has absolutely the same composition and provides the same anti-diarrhea effect at a lower price. The formula of the medication is not new and is not a knowhow of a single company so there is no reason for any Loperamide-based medication to be expensive. All medicines that have in their composition Loperamide are equal in effect and are all properly tested and approved only if they correspond to the original formula. It is a policy of World Health Organization to make all modern medications available all around the world at accessible prices. So you don’t need to worry that the drug with a different name on the package would be less effective than the one with the high price.
When can you buy Generic Imodium?
Imodium or Loperamide is an over-the-counter medication that you can buy without consulting a doctor if you have diarrhea caused by changes in your meal intake regimen or qualitative changes in your diet, diarrhea occurred as a result of a violation of metabolism and absorption, as well as allergic, emotional, medicinal, radiation genesis. Besides, you can buy Loperamide and use it as an additional means in diarrhea caused by infection or if you have Ileostomy (to reduce the frequency and volume of the stool, as well as to give a consistency of its consistency).
If along with diarrhea you have fever, nausea and/or vomit, or have other negative symptoms, you need to go to a doctor and do tests as these can be signs of a life-threatening infection that requires comprehensive therapy and not only the use of anti-diarrhea medication like Loperamide.
When shouldn’t you use Loperamide?
The medication is contraindicated to be used in certain conditions such as intestinal obstruction, diverticulosis, acute ulcerative colitis, pseudomembranous colitis caused by the use of broad-spectrum antibiotics; other conditions in which intestinal peristalsis suppression is inadmissible such as acute dysentery (especially in the presence of blood in the stool and accompanied by fever) and other infections of the gastrointestinal tract. Loperamide also must not be used if you are allergic to the medication and must not be administered to children younger than six years and pregnant women.
Besides the strict contraindications, Imodium is not encouraged to be utilized in severe liver dysfunction and in kids aged from two to twelve years is the intake is not made at a hospital where it is admissible to use the drug under a pediatrician’s supervision.
What adverse effects can Imodium or Loperamide use cause?
Before you buy Generic Loperamide and start using it, especially if you plan to use the medication continuously, you should know that the likelihood of adverse reactions rises the longer you use the pills. The possible negative symptoms include discomfort and pain in the lower abdomen, dyspepsia, nausea and vomiting, ileus, flatulence, constipation, defecation, megacolon and toxic megacolon, extremely rarely can develop intestinal obstruction; you can also start suffering from increased fatigue, headache, sleepiness or insomnia, dizziness, difficulty of urination, erectile dysfunction, blurred vision, and others.
The hypersensitivity reactions in which you must stop using the pills are skin rash, swelling, anaphylaxis, and others. If you suffer from severe allergic reactions such as swelling of the tongue or others, seek emergency help.
How does Imodium interact with other medicines or substances?
It is not recommended to take Loperamide along with atropine and other cholinolytic drugs (to avoid mutual enhancement of effects), erythromycin, metoclopramide, and others.
If you use Cholestyramine, you should take it at least two hours before you take Imodium.
During the clinical trials, it was established that the high doses of Loperamide (around 16 mg) taken along with drugs-inhibitors of P-glycoproteins (quinidine, Ritonavir) leads to an increase in the level of Loperamide hydrochloride in plasma 2-3 times.
If you take any medications along with Loperamide, especially, if you plan to use the anti-diarrhea medication for a long time, it is preferable to consult a doctor.
How to take Generic Loperamide?
There is no difference in the dosage recommendations whether you order Imodium or Loperamide or the medication with another name as long as the active agent is Loperamide.
The pills are taken without chewing and are washed down with a lot of water.
The medication can be used at home for the adults and kids older than six years.
For acute diarrhea, take two pills if you are an adult or give a single pill to a kid with the symptom. Then, after every loose stool take 1 tablet. The max course of treatment for acute diarrhea is up to five days. You don’t need to take the pills if the symptoms are gone. If diarrhea persists within two days after you started taking the pills, you need to discontinue their use of the drug and seek medical assistance.
Chronic diarrhea is treated (if your healthcare provider approves and the tests do not show any conditions that require alternative treatment) with 2 pills (4 mg) every day at the same time in adults. For kids, under the same conditions, the daily dosage is 1 pill a day. The daily dose can be adjusted so that the frequency of solid bowel movements is 1-2 times a day. It is usually achieved with a maintenance dose of 1-6 capsules daily.
The max daily dosage for an adult in chronic diarrhea is 8 capsules or 16 mg. For children, the max dosage depends on the body mass and should not exceed 3 pills per 20 kilograms of the body weight.
Overdose signs and treatment
The signs of an overdose include suppression of the nervous system, impaired coordination, sleepiness, muscle hyper tone, and others. Children are more susceptible to the adverse effects from the part of the nervous system than adults in an overdose.
The treatment requires the discontinuation of the medication use, gastric lavage. As an antidote, naloxone can be used.
The first thing you can do at home if you overdosed is induce vomiting and then take activated charcoal. If the nervous system symptoms occur, you need to seek medical assistance.
If you order Loperamide for your child, you need carefully give him or her pills to avoid overdosing as kids can suffer from an overdose more severely than adults.
Where can you buy Imodium?
You can get the medication over-the-counter almost everywhere but if you need to take the pills continuously and you want to save, the best option for you is to order Generic Imodium from our online pharmacy.
Shipping of Imodium
The medication sold on this webpage as well as all drugs that we sell are shipped internationally. If your order is over 170 USD, you will also enjoy free shipping to your doorstep.
Our doctor prescribes Loperamide online for free, and there is no doctor’s consultation fee.
All orders of Loperamide arrive in discrete unmarked parcels. We leave the shipment description blank.