What is Obestat? How to Treat with Generic Obestat.
More facts about Generic Obestat (Obestat 15 mg):
Generic Obestat (Obestat 15 mg) guide:
What are the pills you can buy under the commercial name Obestat? When are these pills used?
The brand name Obestat is utilized for the active substance named Sibutramine. Sibutramine is the formulation that helps people to lose excessive weight as it acts as appetite suppressing agent. It was discovered back in 1988 and is now made by different companies.
However, if you are slightly chubby you should not buy Obestat as it is developed to assist individuals who suffer from the obesity and have the body mass index over thirty or twenty-seven but with the accompanying diseases such as diabetes type II, and other disorders associated with the high body mass.
How Obestat renders its effect?
The medication’s effect on weight loss is due to its inhibitory effect on the reuptake of serotonin and noradrenaline. Through this, Obestat lowers the appetite and enhances the sense of saturation in the smaller intake of food, increases thermogenesis, and contributes to the reduction on the long-stored fat tissue.
The weight reduction that occurs with the use of Obestat is associated by the elevation of the high-density lipoproteins (“good” cholesterol), the lowering of total cholesterol, triglycerides, low-density lipoproteins, and uric acid.
In people with normal blood pressure, during the therapy is observed an insignificant increase in the arterial pressure. But if the drug is combined with the inhibitors of microsomal oxidation, the risk of cardiovascular negative reactions increases.
When the medication is taken, 77% of it is quickly absorbed from the digestive tract. It is then metabolized in the liver with the effect of the CYP3A4 enzyme with the formation of two active metabolites.
The maximum concentration of the medication in the blood plasma is achieved in three to four hours. The intake of the medication with food lowers the effect of metabolites and increases the time of the maximum concentration achievement.
The equilibrium concentration of active metabolites in the blood is reached within 4 days after the start of treatment and approximately 2 times higher than the plasma level after taking a single dose.
The active metabolites undergo hydroxylation and conjugation with the formation of inactive metabolites which are excreted mainly by the kidneys.
When is Obestat contraindicated to be used?
You must not buy Generic Obestat if you are sensitive to the drug’s components, if you have organic causes for the weight gain (for instance, hormonal imbalance), if you are diagnosed with anorexia or bulimia, mental illnesses, Tourette's syndrome, any heart disease, any diseases of the blood vessels, veins, or arteries; raised blood pressure, thyroid gland dysfunction, severe impairment of the liver or renal function, enlargement of the prostate accompanied by residual urine, atonic bladder, glaucoma, alcohol or drug dependence, concurrent administration or period less than two weeks after the abolition of MAO inhibitors or other drugs acting on the CNS, as well as other drugs to reduce body weight.
Besides, the medication is highly not encouraged to be used during pregnancy or breastfeeding period because its safety in these categories of patients hadn’t been sufficiently studied.
The limited, cautious, or undesired use of the medication is in the presence of epilepsy, motor-verbal tic (involuntary muscle contraction, articulation impairment), in children and the elderly people (safety and efficacy in children under 18 years of age and in people older than 65 years is not defined).
Is there a difference when you buy generic or the branded drug?
There is no difference in the efficiency and safety of the medications with the same composition and effect if they are made by different manufacturers. However, if you buy Sibutramine under a new to you commercial name, make sure to check that the active substance of the medication is Sibutramine and the amount of it per pill is the same as in the original drug.
What adverse effects can Obestat use cause?
The most common adverse effects that are associated with the drug use are a headache, anorexia, insomnia, dry mouth, constipation, and blood pressure elevation. Other side effects such as nausea, vomiting, allergic reaction, and others can also develop. If you start developing any side effects and especially the ones related to the blood pressure or heart function or allergic reactions, stop using the pills immediately and seek medical consultation.
Can Obestat be taken with other medicines?
When you buy Generic Sibutramine, you need to check that you don’t use any medicines that must not be used with it. They include MAO inhibitors, antidepressants, neuroleptics, tryptophan, and other medicines used to lower the body weight.
The inhibitors of microsomal oxidation, including inhibitors of CYP3A4 cytochrome P450 such as ketoconazole, erythromycin, cyclosporine, and others reduce the clearance of Sibutramine and can contribute to the development of cardiovascular adverse effects. Therefore, they are not recommended to be taken along with this weightless drug.
The medication is also not advised to be used with medications that increase serotonergic transmission as it can cause the occurrence of a rare yet dangerous condition called serotonin syndrome that is characterized with agitation, increased sweating, diarrhea, fever, arrhythmia, seizures, and so on.
It is not recommended to take Obestat or its analogs along with any medicines that contribute to the elongation of the QT interval, medications that contain ephedrine, phenylpropanolamine, and pseudoephedrine.
If you use any other medications not listed here, please consult your doctor before you order Obestat and start taking the pills to make sure that you won’t be using any potentially dangerous combination of medicines.
How should you use Obestat?
First of all, before you start the therapy with the drug, you need to undergo a comprehensive checkup to exclude all conditions in which the use of this medicine is contraindicated. Secondly, you need to consult your therapist of nutritionist whether it is safe or not to take Obestat with the other preparations that you use if you use any. Then, if you don’t have any contraindications for its use, you can order Generic Obestat and use it by one 10 mg pill once a day in the morning before a meal. If you develop mild to moderate side effects, you can lower the dose to 5 mg a day.
If the effect of the medication is insufficient but you don’t suffer from any side effect, after four weeks of the therapy, the daily dose can be elevated to 15 mg taken once a day. The maximum treatment course duration is one year without interruptions (the period of use of 15 mg a day should be short).
Please note that the use of the mediation is reasonable only in the case that all other measures to lower your weight failed or deemed insufficiently effective. The treatment must be undergoing under a supervision of a doctor who has an experience of obesity treatment by a complex therapy, i.e. dietary means, eating habits change, lifestyle change, and so on.
Precautions to follow during the therapy with Obestat
During the therapy with the medication, it is important to monitor the arterial pressure and heart frequently to notice if the medication contributes to any cardiovascular adverse effects timely.
The medication must be cautiously used in hypokalemia and hypomagnesemia, and in a malfunction of the liver and kidneys of mild and moderate severity.
If during the therapy you develop chest pains, progressing shortness of breath, and swelling of the legs, it can be a signed of lung hypertension and requires medical assistance.
Women of childbearing age must ensure that they use reliable birth control means while taking Obestat as the mediation is prohibited to be used in pregnant women.
The use of the drug can reduce salivation and contribute to the development of caries, periodontal diseases, candidiasis, and discomfort in the oral cavity. During the period of treatment, it is recommended to limit the use of alcohol.
Obestat is not recommended to be used by drivers or people whose work requires increased concentration of attention.
If you overdose, you can develop severe side effects. The most common ones are irregular heartbeat; elevate blood pressure, headache, and dizziness.
At home you can take a sorbent drug if you have it, then, seek medical assistance.
Where can you buy Obestat?
The drug is available currently only in some countries so it’s safe to say that the best place to get is an online drugstore situated in one of those countries. We offer you to order Sibutramine at an affordable price and with the delivery to your doorstep wherever you live.
Shipping of Obestat
Order your pills without any fear you will get your parcel wherever you live as we ship worldwide.
Our doctor prescribes Obestat online for free, and there is no doctor’s consultation fee.
All orders of Obestat arrive in discrete unmarked parcels. We leave the shipment description blank.