Progynova (Estradiol Valerate 1 mg)
Brand name:
Progynova
Generic name:
Estradiol Valerate
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Progynova (Estradiol Valerate) is a well-established estrogen medication widely used in womens health to support hormonal balance. It contains estradiol valerate, a synthetic form of estrogen that is converted in the body into estradiol, the primary female sex hormone. This medication is commonly prescribed to help manage estrogen deficiency, especially during menopause or after ovarian dysfunction.
Progynova helps relieve vasomotor symptoms such as hot flashes, night sweats, and mood instability, while also supporting bone density maintenance and overall quality of life. By restoring physiological estrogen levels, it contributes to healthier reproductive tissues and improved hormonal regulation.
This drug is often used as part of hormone replacement therapy (HRT) and may also play a role in specific gynecological or reproductive treatment protocols under medical supervision. Progynova is valued for its predictable absorption, stable hormonal effect, and long history of clinical use, making it a trusted option for estrogen support when indicated.
Manufacturer:
Active ingredients:
Progynova (Estradiol Valerate) is a clinically proven estrogen therapy containing the active substance Estradiol Valerate with the chemical formula C23H32O3, designed to restore estrogen balance, support hormone replacement therapy, relieve menopausal symptoms, improve endometrial health, and help manage estrogen deficiency–related conditions through stable and predictable hormonal action.
Indications:
- Menopausal Symptoms: Progynova is indicated for the relief of estrogen deficiency symptoms during natural or surgical menopause, including hot flashes, night sweats, vaginal dryness, mood changes, and sleep disturbances;
- Hormone Replacement Therapy (HRT): This medication is used as part of estrogen replacement therapy to restore physiological estrogen levels in women with reduced or absent ovarian function, helping maintain overall hormonal balance;
- Hypoestrogenism: Progynova is prescribed in conditions where the body produces insufficient estrogen, such as ovarian failure, ovarian removal, or congenital estrogen deficiency, supporting normal endocrine function;
- Prevention of Postmenopausal Osteoporosis: Estradiol Valerate helps reduce bone loss associated with estrogen deficiency, lowering the risk of fractures in postmenopausal women when other treatments are unsuitable;
- Endometrial Preparation in Assisted Reproductive Techniques: Progynova is commonly used to promote adequate endometrial growth and thickness in women undergoing IVF or other fertility treatments;
- Menstrual Cycle Regulation: The drug may be used to regulate menstrual cycles in cases of hormonal imbalance where estrogen supplementation is clinically required;
- Urogenital Atrophy: Progynova helps improve symptoms related to estrogen deficiency affecting the urinary and genital tract, such as dryness, irritation, and discomfort.
- Hormone Replacement Therapy (HRT): This medication is used as part of estrogen replacement therapy to restore physiological estrogen levels in women with reduced or absent ovarian function, helping maintain overall hormonal balance;
- Hypoestrogenism: Progynova is prescribed in conditions where the body produces insufficient estrogen, such as ovarian failure, ovarian removal, or congenital estrogen deficiency, supporting normal endocrine function;
- Prevention of Postmenopausal Osteoporosis: Estradiol Valerate helps reduce bone loss associated with estrogen deficiency, lowering the risk of fractures in postmenopausal women when other treatments are unsuitable;
- Endometrial Preparation in Assisted Reproductive Techniques: Progynova is commonly used to promote adequate endometrial growth and thickness in women undergoing IVF or other fertility treatments;
- Menstrual Cycle Regulation: The drug may be used to regulate menstrual cycles in cases of hormonal imbalance where estrogen supplementation is clinically required;
- Urogenital Atrophy: Progynova helps improve symptoms related to estrogen deficiency affecting the urinary and genital tract, such as dryness, irritation, and discomfort.
Benefits:
- Relief of menopausal symptoms: helps reduce hot flashes, night sweats, and sudden heat episodes caused by estrogen deficiency;
- Hormonal balance restoration: replenishes estrogen levels in women with natural or surgical menopause, supporting overall endocrine stability;
- Improved emotional well-being: may reduce mood swings, irritability, and emotional instability linked to low estrogen levels;
- Support for bone health: helps slow bone density loss and lowers the risk of osteoporosis associated with estrogen decline;
- Endometrial support: promotes healthy endometrial development, especially important in fertility treatments and assisted reproductive protocols;
- Urogenital health improvement: reduces vaginal dryness, discomfort, and atrophic changes in estrogen-sensitive tissues;
- Menstrual cycle regulation: supports normalization of cycles in women with hormonal imbalance when estrogen supplementation is required;
- Cardiovascular support: contributes to healthier lipid profiles and vascular function when used appropriately in hormone therapy;
- Predictable hormonal action: provides stable and controlled estrogen delivery with well-studied pharmacokinetics;
- Long clinical history: widely used and researched, offering a reliable option for estrogen replacement when clinically indicated.
- Hormonal balance restoration: replenishes estrogen levels in women with natural or surgical menopause, supporting overall endocrine stability;
- Improved emotional well-being: may reduce mood swings, irritability, and emotional instability linked to low estrogen levels;
- Support for bone health: helps slow bone density loss and lowers the risk of osteoporosis associated with estrogen decline;
- Endometrial support: promotes healthy endometrial development, especially important in fertility treatments and assisted reproductive protocols;
- Urogenital health improvement: reduces vaginal dryness, discomfort, and atrophic changes in estrogen-sensitive tissues;
- Menstrual cycle regulation: supports normalization of cycles in women with hormonal imbalance when estrogen supplementation is required;
- Cardiovascular support: contributes to healthier lipid profiles and vascular function when used appropriately in hormone therapy;
- Predictable hormonal action: provides stable and controlled estrogen delivery with well-studied pharmacokinetics;
- Long clinical history: widely used and researched, offering a reliable option for estrogen replacement when clinically indicated.
Analogs:
Climaval, Cyclo-Progynova, Delestrogen, Estradiol Valerate, Estrofem Valerate, Estrogen Depot, Estroval, Femogyn Valerate, Neofollin, Progynon Depot, Primogyn, Valergen, Valestrin.

