More facts about Generic Atacand (Candesartan 8 mg):
Generic Atacand (Candesartan 8 mg) guide:
Generic Atacand (Candesartan) is a medication used for elevated blood pressure lowering. It belongs to the class of angiotensin 2 receptor antagonist. The drug also shows benefits in the reduction of mortality in congestive heart failure.
When should the generic Atacand be used?
You can buy Generic Atacand (Candesartan) and use it as prescribed by your doctor or as said in the instruction if you suffer from hypertension, congestive heart failure, or disturbance of systolic function of the left ventricle (as an additional therapy to angiotensin-converting-enzyme inhibitors or in case of intolerance of angiotensin-converting-enzyme inhibitors).
What is the mechanism of action of Atacand (generic Candesartan)?
The active substance of Atacand, Candesartan, is a selective non-peptidic blocker of AT1-receptors of angiotensin II. It prevents the development of effects caused by angiotensin II. It dilates (widens) blood vessels and arteries, contributes to the decrease in the overall peripheral resistance of the blood vessels, promotes an increase in glomerular filtration rate and renal blood flow, as well as an increase in plasma renin activity and angiotensin I and angiotensin II concentrations.
Unlike angiotensin-converting enzyme inhibitors, the drug does not affect the metabolism of bradykinin (a peptide that causes blood vessels extension) and other peptide compounds, which explains its better tolerability. Due to a decrease in the total peripheral resistance and a decrease in blood pressure, the drug somewhat reduces the load on the myocardium.
The blood lowering effect is achieved within 60 minutes after the pill intake and is maintained within 24 hours.
The drug is transformed into an active form into the intestinal mucosa. The maximum concentrations in the blood plasma are observed within 3-4 hours after the drug intake.
The effectiveness of the drug is not influenced by food. The drug is excreted with feces.
How to use the drug?
First of all, it’s worth noting that medication comes in different forms. The standard form is simple Atacand but there is an enhanced formula called Atacand HCT which is a combination drug in which the active substance Candesartan is accompanied with the diuretic drug hydrochlorothiazide. The dosages of the medications vary. Therefore, you have to clarify with your doctor what form of the medication you need before you buy Generic Atacand (Candesartan).
The generally recommended dosages are the following:
- Hypertension treatment in adults: the staring daily dosage is 16 mg taken orally once a day. Further and adjustment can be made and the maintenance dosage from 8 to 32 mg a day orally in divided doses can be used. The maximum dosage of Atacand or Generic Atacand for adults with normal kidney function is 32 mg a day.
The accumulated blood pressure lowering effect is usually observed within 2 weeks of the therapy after which your doctor can decide whether you need to lower the dosage, increase it or stick to the initial one.
- Congestive heart failure in adults: the starting dosage is 4 mg of the drug taken orally once a day. The dosage can be doubled after 2 weeks of intake if the desirable effect is not achieved and the drug is well tolerated. The optimal daily dosage is 32 mg in one intake but the adjustments to reach this dosage should be made not sooner than every 2 weeks.
- Hypertension treatment in children: for children from 1 to 6 years of age, the starting dosage should be 0.2 mg per kilogram of the body weight taken orally in one or two intakes. The standard therapeutic dosage is 0.05 to 0.4 mg per kilogram of the body weight taken in one or two intakes.
For children older than 6 years and younger than 17 years who weight less than 50 kg, the starting therapeutic dosage is from 4 to 8 mg a day taken orally in a single or two intakes. Further the dosage can be adjusted in the range from 2 to 16 mg a day taken in one or two intakes.
For the children from 6 to 17 years who weight 50 kilograms or more, the starting dosage is from 8 to 16 mg taken in one or two intakes a day. Later the dosage can be either lowered to 4 mg a day or increased up to 32 mg a day in one or two intakes. The dosage adjustments are made by the doctor based on the assessment of the patient’s tolerance of the drug and the effect achieved.
The dosages for people who suffer from stenosis of the renal artery, stenosis of the aortic and mitral valve, as well as primary hyperaldosteronism, and diabetes mellitus are chosen individually. Also, those people who underwent renal transplantation must use the drug only under a doctor’s supervision.
Whom the drug is contraindicated?
You should not buy Generic Atacand (Candesartan) and use it if you are pregnant, breastfeed or have allergy to the pills’ components.
People with severe liver or kidney dysfunction are also not advised to use the medication.
What side effects can Atacand (Candesartan) cause?
As any other medication, the drug can cause a variety of side effects such as excessive decrease in the blood pressure, including postural hypotension, leukopenia, agranulocytosis, neutropenia, cardiac arrhythmias, thrombocytopenia, aplastic and hemolytic anemia, vertigo, headache, disturbance of sleep and wakefulness regime, paresthesia, depressive conditions, convulsions, nausea, decreased appetite, stomach irritation, constipation, diarrhea, hepatitis, decreased liver function, increased liver enzymes production, cholestasis, Quincke's edema, itchy skin, photosensitivity; an increase in the potassium level in the plasma, hyponatremia, pain in the muscles and joints, decreased kidney function, a violation of the water-electrolyte balance, reduced visual acuity. In addition, the development of interstitial nephritis, an increase in the level of glucose and uric acid in the blood plasma can be observed.
With what medications the drug should not be combined?
The medication should not be combined with potassium-sparing diuretics and potassium-containing preparations, nonsteroidal anti-inflammatory drugs, lithium, and others. If you are not sure whether the drugs you use can negatively interact with Atacand, consult your doctor about them.
What should you do in the overdose with Atacand (Candesartan)?
If you overdosed with the drug, you should immediately seek medical assistance. The overdose is manifested in general weakness, dizziness, loss of consciousness, and so on as a result of the extremely lowered blood pressure. The doctor would need to give you a symptomatic treatment and monitor your vital functions so it is important to agree for the hospitalization.
Is there a difference between the brand-name drug and the generic?
No, there is no difference. Both brand Atacand and Generic Atacand are based on the active substance called Candesartan and are made using the same chemical formula. Therefore, you can safely buy Generic Atacand and save the money you would need to pay for the brand name if you bought the widely advertised drug.
Where to buy Atacand (Candesartan)?
The best way to buy Atacand is at our online drugstore. Not only we offer you to buy exactly the same medication as your local drugstores but several times cheaper, we also offer you the high-quality generics that are identical to the brand-name drug at even lower price!
Besides that, if you buy the medication from the pharmacies in the U.S., you would need to visit your doctor for a prescription every time you need a new package of pills. With our online pharmacy you can forget about it as we sell the drug over-the-counter based on the laws of the country we are operating from.
Atacand (Candesartan) shipping by Rxshop
If you are afraid that we might not ship to your country – don’t be! We ship medications that we sell worldwide. We offer two shipping options: standard and express and both of them are coming with tracking numbers. The standard delivery takes up to 25 days while express is only 7 to 12 days. And the good news is that if you buy in total for $170 per a single order, your pills will be shipped at our expense.
Our doctor prescribes Candesartan online for free, and there is no doctor’s consultation fee.
All orders of Candesartan arrive in discrete unmarked parcels. We leave the shipment description blank.