Generic Adalat (Nifedipine 30 mg) guide:
Generic Adalat (Nifedipine) is a medication used for hypertension management. The drug relieves tension from the heart and contributes to better myocardium supply with oxygen through dilation of coronary arteries and peripheral blood vessels.
When should the drug be used?
Generic Adalat (Nifedipine) is primarily prescribed for people with arterial hypertension, but can be also used for stable angina (stress angina); angiospastic angina; prevention of migraine attacks; renal, cholelithiasis, intestinal colic and other conditions which require strong antispasmodic effect, Raynaud's syndrome, pulmonary hypertension, and obstructive lung disease.
What is the mechanism of action of Generic Adalat (Nifedipine)?
The medication blocks calcium channels and inhibits the flow of calcium ions through the membrane of cardiomyocytes and smooth muscles that line blood vessels. This leads to the lowered accumulation of calcium within the cells and reduces overall peripheral vascular resistance. This leads to the lowered load of the heart and increased supply of oxygen to the myocardium.
The inhibition of income and accumulation of calcium ions in cardiomyocytes (cardiac muscle cells) prevents the depletion of the energy reserves of the myocardium and provides a protective effect on the cardiac muscle.
Generic Adalat (Nifedipine) also lowers blood pressure and pains in the chest associated with myocardial hypoxia; it also improves the post-stenotic coronary blood flow in atherosclerosis.
The release of the active substance from the pills is quite slow which means that the effect of the drug is maintained within 24 hours after the pill intake.
The maximum stable effect of blood pressure lowering in achieved after 3-4 days of intake. The chest pains usually are lowered within 3-4 weeks after the start of the therapy with the drug.
In the beginning of the therapy, the heart rate and cardiac output can be lowered due to the activation of baroreceptors (sensors located in the blood vessels) but in the long-term therapy, they return to the values present before the start of the therapy.
How to use the drug Generic Adalat (Nifedipine)?
Before you buy Generic Adalat (Nifedipine), you should get a proper diagnosis to be sure that the medication is what you really need and that it is not contraindicated for you. Before the treatment start, your doctor should inform you about the desirable (normal) blood pressure and heart rate for you during the therapy with Nifedipine-based medications. If after the first drug intake you experience pain or chest tightness, then you need to consult your doctor before taking the next dosage. If during the therapy you have frequent, potent and lasting chest pains both at rest and exercising, you should also inform your doctor.
The dosage is chosen individually for various conditions and their severity but in general, the therapy is started with 40 mg (one pill) taken once a day. If the dosage is ineffective, it can be gradually increased to 80 mg a day taken into two intakes.
In case a patient forgot to take the pill and its already time for the next intake, he or she should skip the missed dosage intake and take the next single dosage instead. The pills should be swallowed entirely with a whole glass of water.
People with liver and kidney impairment usually do not require dosage adjustment.
Whom the drug is contraindicated?
You should not buy Generic Adalat (Nifedipine) and inform your doctor if he or she recommends you the drug if you have one of the following conditions: cardiogenic shock, porphyria, severe aortic stenosis, arterial hypotension, severe heart failure in decompensation, acute myocardial infarction, allergy to Nifedipine or other components of the pill, or hypersensitivity to dihydropyridines.
The medication is also contraindicated for children and teenagers below 18 years of age. There is no sufficient information on the medication safety for pregnant and breastfeeding women therefore, the drug is contraindicated for them to date.
When you undergo the therapy with the drug, you should avoid drinking grapefruit juice and alcohol.
If you need to stop taking the pills, the dosage should be lowered gradually. People with hypertension may experience elevated blood pressure upon the withdrawal.
What side effects can Generic Adalat (Nifedipine) cause?
The drug use can cause headaches, redness of the face, edema of the ankles, dizziness, and tiredness.
The rarest adverse reactions that can still occur are violation of the heart rate, chest pains, nausea, heartburn, constipation, diarrhea, skin rash, itching, muscle cramps, and others.
With what medications the drug should not be combined?
If the drug is combined with other medications that lower blood pressure including diuretics and others, there is a synergic effect on the blood pressure lowering.
When the drug is combined with Fentanyl, Cimetidine, Tricyclic antidepressants, and Ranitidine excessive blood pressure lowering can be observed.
Rifampicin induces the production of liver ferments and accelerates the metabolism of Nifedipine which can lead to the lowering of the latter drug effect.
If you use calcium-containing preparations or additives, the therapeutic effect of the blood pressure medication is reduced.
What should you do in the overdose with Generic Adalat (Nifedipine)?
In the overdose of the drug, the following symptoms can occur: excessive arterial hypotension, tachycardia, bradycardia (slow heart rate), arrhythmia, nausea, vomiting, weakness, redness of the skin, dizziness, drowsiness, color perception disorders, metabolic acidosis, convulsions, and loss of consciousness.
If the patient is conscious, it is advised to induce vomiting. Further, symptomatic treatment under a doctor’s supervision is advised.
Is there a difference between the brand-name drug and the generic?
There is no difference between the drugs’ compound, formula, and therefore, their effect. Generic medications are simply made by other pharmaceutical companies that have to register different names than the original brand name for them. All generic medications undergo thorough testing for compliance with the original drug as well as safety and effectiveness tests. They are cheaper because they are made using already developed formula and usually are produced outside the U.S. where drug manufacturing requires tremendous expenses.
Where to buy Adalat or Generic Adalat (Nifedipine)?
If you have a prescription from your doctor, you can buy the drug at your local nearby drugstore. But many people choose to purchase the medication online. First of all, such pharmacies like ours sells the same drugs much cheaper because we do not spend a lot of money on commercial spaces in the U.S. Secondly, to buy Generic Adalat (Nifedipine) from our online drugstore you don’t have to go to your doctor for a prescription as we are located in the country where the drug is sold over-the-counter and it is an absolutely legal practice to buy the drug you need abroad without Rx and receive it in the U.S.
We sell both brand-name medication and its generic version. If you have trouble choosing the drug, contact our customer support managers for help.
Generic Adalat shipping by Rxshop
Even though you have to pay for the delivery of the medication, it will still cost you less money than if you bought it at your local drugstore and paid your doctor for a visit to get the prescription. Moreover, if you order pills for $170 or more, we will ship the pills free of charge.
We have two delivery options: standard which takes from 14 to 25 days and express which is from 7 to 12 days. Naturally, express shipping is more expensive but opting for it you will have the tracking number to see where your drugs are at the moment and the parcel will be shipped to your doorstep by the courier. You can find out more about our shipping policy in the respective section of our website.
Our doctor prescribes Nifedipine online for free, and there is no doctor’s consultation fee.
All orders of Nifedipine arrive in discrete unmarked parcels. We leave the shipment description blank.